A common variant in the adiponectin gene on weight loss and body composition under sibutramine therapy in obesity
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چکیده
منابع مشابه
A common variant in the adiponectin gene on weight loss and body composition under sibutramine therapy in obesity
In this study, we aimed to explore whether a common single nucleotide polymorphism (SNP), rs266729 (-11,377C > G), in the adiponectin C1Q and collagen domain containing (ADIPOQ) gene could influence weight reduction and fat change under sibutramine therapy in an obese population. There were 131 obese Taiwanese patients, including 44 in the placebo group and 87 in the sibutramine (10 mg daily) g...
متن کاملSibutramine plus meal replacement therapy for body weight loss and maintenance in obese patients.
OBJECTIVE Our objective was to assess the efficacy and safety of sibutramine with a low-calorie diet (LCD) and commercial meal-replacement product in achieving weight loss and weight-loss maintenance in obese patients. RESEARCH METHODS AND PROCEDURES Eight U.S. centers recruited 148 obese patients for a 3-month comprehensive weight-loss therapy (Phase I) comprising daily sibutramine 10 mg + L...
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Background: Obesity is a very common disorder resulting from an imbalance between food intake and energy expenditure, and it has a substantial impact on the development of chronic diseases. The aim of this study was to examine the association of INSIG2 (rs7566605) gene polymorphism with obesity and obesity associated phenotypes in North Indian subjects. Methods: The variants were investig...
متن کاملObesity & Weight Loss Therapy
Lessons Learned from a Community Based Lifestyle Intervention for Youth at Risk for Type 2 Diabetes Eva M Vivian1*, Lisa H Colbert2, Patrick L Remington3 1University of Wisconsin-Madison, School of Pharmacy, Madison, USA 2Departments of Kinesiology and Population Health Sciences, 2035 Gymnasium-Natatorium, 2000 Observatory Drive, Madison, USA 3UW School of Medicine and Public Health, Health Sci...
متن کاملObesity & Weight Loss Therapy
Type 2 Diabetes Mellitus (T2DM) is the most common and costly endocrine disease [1] which is associated with increased morbidity and premature death, especially from cardiovascular diseases, myocardial infarction and stroke [2]. The prevalence of T2DM has increased dramatically over the past two decades. According to the most recent survey, the number of people who are currently affected by thi...
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ژورنال
عنوان ژورنال: Clinical Pharmacology: Advances and Applications
سال: 2010
ISSN: 1179-1438
DOI: 10.2147/cpaa.s8657